Formerly "Weatherfield Comprehensive School", "Weatherfield High School" is the main institution for secondary education in Weatherfield. The school specialises in the 11-16 age group, although some pupils have sat their A-Level examinations, which would suggest that the school has Sixth (VI) Form facilities.

Lucille Hewitt was the first character to sit her O-Level examinations at the newly formed Weatherfield Comprehensive in 1965.

he school was created by the amalgamation of the Weatherfield School for Girls' and the Weatherfield Boys' School.[25]

The school rarely featured until Ken Barlow returned to teaching in 1991, taking a post in the English department. By this time, Tracy Barlow was a pupil at the school, along with Steve and Andy McDonald and Nick Tilsley. Derek Wilton worked as a caretaker at the school for a period in 1992. The school was referred to as 'Weatherfield Comp' in many scripts. Since 2004, references to 'Weatherfield Comp' have ceased and the school has started to be known as 'Weatherfield High'.

Other former pupils include Jenny BradleyToyah BattersbySarah-Louise PlattCandice StoweTodd Grimshaw, Aiden Critchley,Rosie Webster and Craig Harris. In 2004, Violet Wilson was identified as a former pupil of Ken Barlow and sometimes still referred to him as "sir". Sophie WebsterChesney Battersby-BrownSian Powers and Ben Richardson all have left the school after taking their exams in Year 11.

The only resident of Coronation Street attending the school now is Craig Tinker.

Scenes at Weatherfield High School are filmed on location at Hope High School in Salford.