The centre of Weatherfield comprises all streets along Rosamund Street, starting at Curzon Street in the north and ending at Victoria Street in the south.  Places of interest in the town centre are Weatherfield Central Library, the DHSS, Queen's Shopping Precinct, Bessie Street Primary School and Weatherfield Town Hall.Freshco operates the supermarket in the town centre of Weatherfield, having taken over the old Bettabuy store in the 1990s. In an episode Kevin Webster states that one of the postcodes of is Coronation Street is M10 9KZ.

Other streets in the area include Mawdsley Street, Inkerman Street, Crimea Street, Bessie Street, Balaclava Terrace, Jubilee Terrace, Tile Street, Viaduct Street and Queen Street. Weatherfield has a crown court where Tracy Barlow was sentenced to 15 years for the murder of Charlie Stubbs, and a magistrates court where several residents have appeared in the dock including Les BattersbyRita Sullivan, Kevin Webster, Tracy Barlow and Angela Harris. There is also a prison located within the Greater Manchester area.